Determining the mechanism of 3-phosphorylated phosphoinositides production by Salmonella effector SopB

确定沙门氏菌效应子 SopB 产生 3-磷酸化磷酸肌醇的机制

• 批准号: 486156
• 负责人: Ray Jayatee
• 金额: $ 1.27万
• 依托单位: Dalhousie University (Nova Scotia)
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-12-01 至 2023-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=486156&lang=en
• 关键词: 4)P2; 5)P29; Bacterial Infection; Gallbladder Cancer; Lipid Metabolism; Phosphatidylinositol Phosphatase; Phosphatidylinositols; Phosphotransferases; Ptdins(3; Ptdins(4; Salmonella; Signal Transduction

Salmonella is a common bacterium responsible for life-threatening diarrheal diseases and the development of gallbladder cancer, an aggressive carcinoma. The bacterium infects human cells by manipulating the cell's plasma membrane, which is made of phospho

沙门氏菌是一种常见的细菌，可导致危及生命的肠道疾病和胆囊癌（一种侵袭性癌）的发展。这种细菌通过操纵细胞的质膜来感染人类细胞，质膜是由磷酸盐组成的。