Evaluating the Clinical Relevance of Necroptosis in Ischemia Reperfusion Injury in Human Lung Transplants.

评估人肺移植缺血再灌注损伤中坏死性凋亡的临床相关性。

• 批准号: 485913
• 负责人: Main Kimberly L
• 金额: $ 1.27万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-12-01 至 2023-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=485913&lang=en
• 关键词: Cell Death; Human Clinical Samples; Ischemia-Reperfusion Injury; Lung Transplantation; Necroptosis; Primary Graft Dysfunction

Lung transplantation (LTx) is the only curative treatment for patients suffering from end-stage lung diseases. Unfortunately, LTx is limited by the low number of donor lungs accepted by the transplant teams. This low utilization results from the lungs’ hi

肺移植（LTx）是治疗终末期肺部疾病的唯一有效方法。不幸的是，LTx受到移植团队接受的供体肺数量较少的限制。这种低利用率是由于肺的“高”