Investigating the role of Ras mutations in mediating drug resistance to targeted therapies in cancer

研究 Ras 突变在介导癌症靶向治疗耐药性中的作用

• 批准号: 488144
• 负责人: Mukonoweshuro Chantel L
• 金额: $ 1.27万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-12-01 至 2023-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=488144&lang=en
• 关键词: Cancer; Fbxo42; Functional Genomics; Mapk Inhibition; Mapk Signalling; Non-V600 Braf Mutations; Proto-Oncogenes; Ras Mutations; Targeted Therapies; Therapeutic Resistance

The cell is equipped with thousands of tools (i.e., proteins) that regulate different processes, guiding the cell and telling it when and where to perform major tasks such as growth, division, and migration. This is done through tightly-regulated signalli

该单元配备有数千种工具（即，蛋白质）调节不同的过程，引导细胞并告诉它何时何地执行主要任务，如生长，分裂和迁移。这是通过严格控制的信号来实现的