Compound specific isotopes of polar organic molecules in complex mixtures

复杂混合物中极性有机分子的化合物特定同位素

• 批准号: LE240100109
• 负责人: Prof Kliti Grice
• 金额: $ 19.45万
• 依托单位: Curtin University
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2024
• 资助国家: 澳大利亚
• 起止时间: 2024-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE240100109
• 关键词: Compound; specific; isotopes; polar; organic

This project aims to develop a liquid chromatography – isotope ratio mass spectrometry facility for the measurement of stable carbon isotope ratios of individual organic compounds in complex mixtures, most significantly sugars and amino acids. This will be the first such facility in Western Australia, strategically ranked to greatly expand existing world-class capabilities in stable isotope analysis. An important goal of this project is the analysis of sugars in high-value foodstuffs such as honey, to develop a robust method of provenancing and authentication for important export markets. Other outcomes include elucidation of modern and ancient biological and ecological systems through the isotope analysis of natural products from microbes.

该项目旨在开发液相色谱-同位素比质谱设施，用于测量复杂混合物中单个有机化合物的稳定碳同位素比，最重要的是糖和氨基酸。这将是西澳大利亚州第一个此类设施，其战略排名旨在大大扩展稳定同位素分析方面现有的世界一流能力。该项目的一个重要目标是分析蜂蜜等高价值食品中的糖，为重要的出口市场开发可靠的来源和认证方法。其他成果包括通过微生物天然产物的同位素分析阐明现代和古代的生物和生态系统。