Radio Frequency Coil Design for Ultra High Field Magnetic Resonance Imaging
超高场磁共振成像射频线圈设计
基本信息
- 批准号:RGPIN-2019-04743
- 负责人:
- 金额:$ 6.92万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Discovery Grants Program - Individual
- 财政年份:2022
- 资助国家:加拿大
- 起止时间:2022-01-01 至 2023-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Multichannel radio frequency (RF) coil arrays, composed of multiple resonant elements, are a critical component in magnetic resonance imaging (MRI) acquisition. Parallel transmit (pTx) arrays provide individual sensitivity profiles that when used in concert with optimized gradient and RF waveforms can accelerate the traversal of excitation kspace. This principle can be used to accelerate multidimensional selective excitation, perform B1+ or RF shimming to overcome inhomogeneity at ultrahigh field (UHF), or reduce specific absorption rate (SAR). Similarly, parallel receive (pRx) arrays exploit the locally high signal-to-noise ratio (SNR) of surface coils to the MRI signal (B1-) and extend it across a full field of view while simultaneously performing spatial encoding, utilized in accelerated imaging. The electromagnetic fields responsible for exciting spins during RF transmission, as well as receiving signal from the transverse magnetization post-excitation, transition from purely reactive nearfield interaction towards a mixture of both near and far fields as the main magnetic field strength increases. Due to this, electric dipole antennas are finding increasing utility at UHF when compared to more conventional RF loop elements and combinations of loop and dipole array elements into a single RF coil assembly are expected to show performance gains in SAR efficiency per unit B1+ and SNR. The evolution towards using electric dipole elements and/or combining dissimilar elements present a technical challenge. The radiation patterns produced from the electric dipole, in conjunction with its geometry, are limited by the applicability of conventional decoupling methods. This is best demonstrated in densely populated dipole receive arrays where unmitigated coupling and enhanced noise correlations degrade measured SNR, regardless of an increased sensitivity to the sample. We have developed a generalized decoupling approach that allows complex RF arrays of mixed element types and variable coupling coefficients to be efficiently decoupled with a ladder filter approach. Using this approach, we will simulate, design and build multichannel transmit arrays that combine loops and dipoles in a manner that captures as much of the transmit efficiency as possible for human head imaging. Once the hardware is optimized to generate the best B1+ homogeneity via RF shimming, RF pulses will be used to remove the residual inhomogeneity. Real-time pulse optimization has been a challenge, so compromised approaches are currently used. Using B1+ and static magnetic field maps from subjects and from electromagnetic simulations, we will use machine learning approaches to help design the optimal solutions in real-time that take into account RF homogeneity with the added constraints of SAR. In combination, these approaches will surmount the remaining barriers to the adoption of multichannel pTx for 7 T scanners in clinical and basic neuroscience settings.
多通道射频线圈阵列由多个谐振元件组成,是磁共振成像(MRI)采集的关键部件。并行发射(pTx)阵列提供单独的灵敏度曲线,当与优化的梯度和射频波形一起使用时,可以加速激励k空间的遍历。该原理可用于加速多维选择性激发,执行B1+或RF振荡以克服超高场(UHF)的不均匀性,或降低比吸收率(SAR)。类似地,并行接收(pRx)阵列利用表面线圈对MRI信号(B1-)的局部高信噪比(SNR),并将其扩展到整个视场,同时执行空间编码,用于加速成像。在射频传输过程中,电磁场负责激发自旋,以及从激发后的横向磁化接收信号,随着主磁场强度的增加,从纯粹的反应性近场相互作用转变为近场和远场的混合作用。因此,与传统的射频环路元件相比,电偶极子天线在UHF上的效用越来越大,环路和偶极子阵列元件组合成单个射频线圈组件有望在单位B1+的SAR效率和信噪比方面显示出性能提升。向使用电偶极子元素和/或组合不同元素的演变提出了技术挑战。由电偶极子产生的辐射模式及其几何形状受到传统解耦方法适用性的限制。这在密集的偶极子接收阵列中得到了最好的证明,其中未减轻的耦合和增强的噪声相关性降低了测量的信噪比,而不考虑对样品的灵敏度增加。我们开发了一种广义解耦方法,允许混合元素类型和可变耦合系数的复杂射频阵列通过梯形滤波器方法有效解耦。使用这种方法,我们将模拟,设计和构建多通道发射阵列,结合环路和偶极子,以尽可能多地捕获人类头部成像的传输效率。一旦硬件被优化为通过射频振荡产生最佳的B1+均匀性,射频脉冲将被用来去除残余的不均匀性。实时脉冲优化一直是一个挑战,因此目前使用折衷的方法。利用B1+和来自受试者的静态磁场图以及电磁模拟,我们将使用机器学习方法来帮助设计实时的最佳解决方案,同时考虑到射频均匀性和SAR的附加限制。结合起来,这些方法将克服在临床和基础神经科学设置中采用多通道pTx用于7 T扫描仪的剩余障碍。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Menon, Ravi其他文献
Oats-From Farm to Fork.
- DOI:
10.1016/bs.afnr.2015.12.001 - 发表时间:
2016-01-01 - 期刊:
- 影响因子:0
- 作者:
Menon, Ravi;Gonzalez, Tanhia;Watson, Jay - 通讯作者:
Watson, Jay
Recruitment of Black Subjects for a Natural History Study of Intracerebral Hemorrhage
- DOI:
10.1353/hpu.2013.0007 - 发表时间:
2013-02-01 - 期刊:
- 影响因子:1.4
- 作者:
Edwards, Dorothy F.;Menon, Ravi;Kidwell, Chelsea S. - 通讯作者:
Kidwell, Chelsea S.
Menon, Ravi的其他文献
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{{ truncateString('Menon, Ravi', 18)}}的其他基金
Radio Frequency Coil Design for Ultra High Field Magnetic Resonance Imaging
超高场磁共振成像射频线圈设计
- 批准号:
RGPIN-2019-04743 - 财政年份:2021
- 资助金额:
$ 6.92万 - 项目类别:
Discovery Grants Program - Individual
Radio Frequency Coil Design for Ultra High Field Magnetic Resonance Imaging
超高场磁共振成像射频线圈设计
- 批准号:
RGPIN-2019-04743 - 财政年份:2020
- 资助金额:
$ 6.92万 - 项目类别:
Discovery Grants Program - Individual
Radio Frequency Coil Design for Ultra High Field Magnetic Resonance Imaging
超高场磁共振成像射频线圈设计
- 批准号:
RGPIN-2019-04743 - 财政年份:2019
- 资助金额:
$ 6.92万 - 项目类别:
Discovery Grants Program - Individual
Radio Frequency Coil Design for Ultra High Field MRI
超高场 MRI 射频线圈设计
- 批准号:
261701-2012 - 财政年份:2017
- 资助金额:
$ 6.92万 - 项目类别:
Discovery Grants Program - Individual
Radio Frequency Coil Design for Ultra High Field MRI
超高场 MRI 射频线圈设计
- 批准号:
261701-2012 - 财政年份:2015
- 资助金额:
$ 6.92万 - 项目类别:
Discovery Grants Program - Individual
Radio Frequency Coil Design for Ultra High Field MRI
超高场 MRI 射频线圈设计
- 批准号:
261701-2012 - 财政年份:2014
- 资助金额:
$ 6.92万 - 项目类别:
Discovery Grants Program - Individual
Radio Frequency Coil Design for Ultra High Field MRI
超高场 MRI 射频线圈设计
- 批准号:
261701-2012 - 财政年份:2013
- 资助金额:
$ 6.92万 - 项目类别:
Discovery Grants Program - Individual
Radio Frequency Coil Design for Ultra High Field MRI
超高场 MRI 射频线圈设计
- 批准号:
261701-2012 - 财政年份:2012
- 资助金额:
$ 6.92万 - 项目类别:
Discovery Grants Program - Individual
Shedding light on the origin of BOLD
揭示 BOLD 的起源
- 批准号:
261701-2007 - 财政年份:2011
- 资助金额:
$ 6.92万 - 项目类别:
Discovery Grants Program - Individual
Shedding light on the origin of BOLD
揭示 BOLD 的起源
- 批准号:
261701-2007 - 财政年份:2010
- 资助金额:
$ 6.92万 - 项目类别:
Discovery Grants Program - Individual
相似国自然基金
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Radio Frequency Coil Design for Ultra High Field Magnetic Resonance Imaging
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用于多核超极化气体 MRI 的新型射频发射和接收线圈设计可改善肺部成像诊断
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