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Chromatin-binding deubiquitinase MYSM1 as a putative drug target for cMYC-driven B cell lymphoma

Chromatin-binding deubiquitinase MYSM1 as a putative drug target for cMYC-driven B cell lymphoma
染色质结合去泛素酶 MYSM1 作为 cMYC 驱动的 B 细胞淋巴瘤的推定药物靶点
批准号:
478278
负责人:
Nijnik Anastasia
金额:
$55.45万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-03-01 至 2028-03-01

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中文摘要
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英文摘要
Over 10,000 Canadians are diagnosed and ~3000 die from a type of blood cancer known as non-Hodgkin lymphoma each year, and improved therapies for this disease are urgently needed. cMYC is an essential regulator of gene expression in cancer cells. It is hy
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Deubiquitinase MYSM1 as an essential epigenetic regulator of hematopoiesis
  • 批准号:
    472655
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2022
  • 负责人:
    Nijnik Anastasia
  • 依托单位:
Hematopoietic Stem and Progenitor Cells as Mediators of Trained Immunity in Rheumatoid Arthritis
  • 批准号:
    420532
  • 项目类别:
    Operating Grants
  • 资助金额:
    $72.77万
  • 财政年份:
    2020
  • 负责人:
    Nijnik Anastasia
  • 依托单位:
Canada Research Chair - Tier 2 - CIHR Funded
  • 批准号:
    384928
  • 项目类别:
  • 资助金额:
    $36.43万
  • 财政年份:
    2017
  • 负责人:
    Nijnik Anastasia
  • 依托单位:
Chromatin-Binding Factor MYSM1 in B Lymphocyte Development
  • 批准号:
    356802
  • 项目类别:
    Operating Grants
  • 资助金额:
    $48.76万
  • 财政年份:
    2016
  • 负责人:
    Nijnik Anastasia
  • 依托单位:
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