Development of a novel antimicrobial (AM) sprayable clear coating

开发新型抗菌 (AM) 喷涂透明涂层

• 批准号: 561220-2020
• 负责人: Kumar, AyushA
• 金额: $ 1.54万
• 依托单位: University of Manitoba
• 依托单位国家: 加拿大
• 项目类别: Alliance Grants
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=760949
• 关键词: Development; novel; antimicrobial; AM; sprayable

Antibiotic resistance is a global problem that threatens not only our ability to treat infections caused by bacteria, but also our economy. As we steadily exhaust effective antibiotics, preventing the spread of antibiotic resistant bacteria in environments is critical to continue our ability to use existing antibiotics. Polyamyna Nanotech Inc., a Canadian company, has developed a novel antimicrobial (AM) nanotechnology (patent pending) that has shown superior antimicrobial property against multiple antibiotic resistant bacteria. Currently used antimicrobials suffer from selecting for resistant bacteria. We will evaluate antimicrobial compounds being developed by Polyamyna Nanotech Inc. for their ability to select resistant bacteria, uncover the underlying resistance mechanism(s) and optimize the technology accordingly. This work will therefore result in the development of an antimicrobial spray that will prevent the spread of antibiotic resistant bacteria and will not select for resistant bacteria.

抗生素耐药性是一个全球性问题，它不仅威胁到我们治疗细菌感染的能力，而且威胁到我们的经济。随着我们不断耗尽有效的抗生素，防止耐药细菌在环境中传播对于我们继续使用现有抗生素的能力至关重要。加拿大公司Polyamyna Nanotech Inc.开发了一种新型的抗菌(AM)纳米技术(正在申请专利)，该技术已对多种耐药细菌显示出优异的抗菌性能。目前使用的抗菌药在选择耐药细菌方面受到影响。我们将评估Polyamyna Nanotech Inc.正在开发的抗菌化合物选择耐药细菌的能力，揭示潜在的耐药机制(S)，并相应地优化技术。因此，这项工作将导致开发一种抗菌剂喷雾，该喷雾剂将防止抗药性细菌的传播，而不会选择抗药性细菌。