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Expression of mutant KRAS in endothelial cells leads to hypertranscription and altered ribosome biogenesis

Expression of mutant KRAS in endothelial cells leads to hypertranscription and altered ribosome biogenesis
内皮细胞中突变型 KRAS 的表达导致高转录并改变核糖体生物合成
批准号:
493129
负责人:
Khosraviani Negar
金额:
$0.11万
依托单位国家:
加拿大
项目类别:
财政年份:
2023
资助国家:
加拿大
项目状态:
已结题
起止时间:
2023-09-01 至 2024-09-01

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Brain arteriovenous malformation (bAVM) is a vascular disease characterized by tangled blood vessels formed in the brain of children and young adults. Passage of high-pressure blood through the AVM can result in vessel rupture and stroke. Published work f
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Investigating the role of shear-stress and ribosome biogenesis in the formation and maintenance of KRAS-driven brain arteriovenous malformation (bAVM)
  • 批准号:
    458269
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $7.65万
  • 财政年份:
    2021
  • 负责人:
    Khosraviani Negar
  • 依托单位:
Function of CD36 mediated albumin transcytosis across microvascular endothelial cells
  • 批准号:
    406560
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $1.27万
  • 财政年份:
    2018
  • 负责人:
    Khosraviani Negar
  • 依托单位: