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Identification, development and application of novel neuroserpin inhibitors to correct the NGF deficiency in the Alzheimer's disease pathology

Identification, development and application of novel neuroserpin inhibitors to correct the NGF deficiency in the Alzheimer's disease pathology
新型神经丝氨酸蛋白酶抑制剂的鉴定、开发和应用以纠正阿尔茨海默病病理学中的 NGF 缺陷
批准号:
490333
负责人:
Cuello A. Claudio G
金额:
$41.24万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-09-01 至 2026-09-01

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中文摘要
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英文摘要
In the brain of people affected by Alzheimer's disease there is a progressive loss of a brain neurotransmitter system which plays a key role in cognitive functions. The neurons involved in this system (called basal forebrain cholinergic neurons: BFCNs) re
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Microdose lithium as a treatment for brain tauopathy
  • 批准号:
    468055
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    Operating Grants
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    $82.48万
  • 财政年份:
    2022
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Is Early Inflammation in Alzheimer's Disease Driven by Intracellular Amyloid beta Accumulation?
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    344417
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    Operating Grants
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    $79.36万
  • 财政年份:
    2016
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    Cuello A. Claudio G
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Locus coeruleus in Alzheimer's pathology: its impact on early neuroinflammation and amyloid pathology
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    356851
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  • 资助金额:
    $63.53万
  • 财政年份:
    2016
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Studies on the plasticity of CNS cholinergic neurons
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    265516
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  • 负责人:
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海外基金