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Structural and Chemical Biology of Targeted Degraders of NSD2

Structural and Chemical Biology of Targeted Degraders of NSD2
NSD2 靶向降解剂的结构和化学生物学
批准号:
488833
负责人:
Arrowsmith Cheryl H
金额:
$78.02万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-09-01 至 2028-09-01

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中文摘要
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英文摘要
NSD2 is a protein molecule in our cells that interacts with and packages our DNA, to regulate the genes that drive cancer cell survival and spread. When NSD2 activating mutations occur, it leads to widespread changes in how the cell's genome functions and
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Structural and Chemical Biology of Targeted Degraders of NSD2
  • 批准号:
    483396
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2023
  • 负责人:
    Arrowsmith Cheryl H
  • 依托单位:
Characterization and Modulation of Methylation-Mediated Signaling Networks in Health and Disease
  • 批准号:
    354619
  • 项目类别:
    Operating Grants
  • 资助金额:
    $143.26万
  • 财政年份:
    2016
  • 负责人:
    Arrowsmith Cheryl H
  • 依托单位:
Influence of the Microbiome on Epigenetic Mechanisms in Inflammatory Bowel Disease (IBD)
  • 批准号:
    277384
  • 项目类别:
    Operating Grants
  • 资助金额:
    $103.81万
  • 财政年份:
    2012
  • 负责人:
    Arrowsmith Cheryl H
  • 依托单位:
Toward epigenetic therapy for colon cancer
  • 批准号:
    267945
  • 项目类别:
    Operating Grants
  • 资助金额:
    $74.02万
  • 财政年份:
    2012
  • 负责人:
    Arrowsmith Cheryl H
  • 依托单位:
海外基金