Unraveling the role of N-acetyl-aspartate in normal brain function and disease

揭示 N-乙酰-天冬氨酸在正常脑功能和疾病中的作用

• 批准号: FT100100546
• 负责人: Adj/Prof Matthias Klugmann
• 金额: $ 56.65万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-02-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT100100546
• 关键词: Unraveling; role; acetyl; aspartate; normal

The purpose of this project is to define the role of the predominating brain chemical N-acetyl-aspartate for normal nerve cell function and as toxic agent causing neurological illness and severe mental health problems. Findings of this research will enhance the design of novel therapies involving pharmacological and genetic treatment.

该项目的目的是确定占主导地位的脑化学物质N-乙酰基-天冬氨酸对正常神经细胞功能的作用，以及作为引起神经系统疾病和严重精神健康问题的有毒物质的作用。这项研究的结果将加强涉及药物和基因治疗的新疗法的设计。