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Elucidating the principles of translational control and their aberrations in cancer: understanding the role of eIF4E phosphorylation in cancer development and progression

Elucidating the principles of translational control and their aberrations in cancer: understanding the role of eIF4E phosphorylation in cancer development and progression
阐明癌症中翻译控制及其畸变的原理：了解 eIF4E 磷酸化在癌症发生和进展中的作用
批准号：
200024
负责人：
Robichaud Nathaniel
金额：
$1.27万
依托单位：
McGill University
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2010
资助国家：
加拿大
项目状态：
已结题
起止时间：
2010-02-01 至 2011-02-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=200024&lang=en
关键词：
Breast Cancer Cancer Therapy Eif4e Phosphorylation Human Tumor Samples Mouse Models Polysome Profiling Prostate Cancer Translation Initiation Tumor Progression Western Blots

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中文摘要
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英文摘要
Aberrant protein synthesis is critical in the transformation of normal cells into cancerous growths, in part because these cells require more protein synthesis in order to grow faster. One of the proteins involved in protein synthesis, called eIF4E, is mo
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eIF4E phosphorylation and the tumour microenvironment: implications in signalling, invasion and metastasis
eIF4E phosphorylation and the tumour microenvironment: implications in signalling, invasion and metastasis
  • 批准号：
    247712
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $10.93万
  • 财政年份：
    2011
  • 负责人：
    Robichaud Nathaniel
  • 依托单位：
    McGill University
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