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Studies on the defective protein anabolism in human lung cancer: role of insulin resistance, acute-phase response, and gluconeogenesis.

Studies on the defective protein anabolism in human lung cancer: role of insulin resistance, acute-phase response, and gluconeogenesis.
人类肺癌中蛋白质合成代谢缺陷的研究：胰岛素抵抗、急性期反应和糖异生的作用。
批准号：
200357
负责人：
Macadams Jacqueline M
金额：
$1.27万
依托单位：
Macdonald Campus of McGill Univ. (Ste-Anne-de-Bell)
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2010
资助国家：
加拿大
项目状态：
已结题
起止时间：
2010-02-01 至 2011-02-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=200357&lang=en
关键词：
Acute Phase Protein Synthesis Amino Acid Contribution To Gluconeogenesis Effect Of Insulin Resistance On Glucose Metabolism Effect Of Insulin Resistance On Protein Metabolism Euglycemic Hyperinsulinemic Isoaminoacidemic Clamp Study Metabolic Effect

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Protein loss, mostly from muscle, is very common in the advanced stages of lung cancer and this affects the patients' physical function, response to treatment and quality of life. We propose that cancer patients are losing muscle proteins because they ar
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