蜘蛛丝和蚕丝等是自然创造的具有非凡力学性质的生物大分子材料，而甲壳素、纤维素和多糖等是自然界最丰富和被人类广为应用的天然高分子，阐明生物大分子中精确控制的多尺度结构与动力学，进而通过多尺度仿生来制备高性能生物基高分子材料、并实现传统合成聚合物的高性能化是高分子科学重要课题。本项目拟采用多尺度固体NMR并结合其它表征手段，在不同时空尺度上揭示高性能天然生物大分子中的微相分离结构与界面、水与生物大分子的氢键相互作用、大分子的复杂链运动、以及拉伸过程中多尺度结构与动力学的演化规律其对力学性能的影响，由此建立对高性能生物材料结构-性能关系的深入认识。在此基础上，通过多尺度的仿生分子设计来制备系列基于壳聚糖和多嵌段聚氨酯的高性能仿生高分子材料，推动我国生物基高分子与合成聚合物材料高性能化领域的基础与应用研究。

Spider silk and silkworm silk are the most attractive biomaterials with extraordinary mechanical properties created by nature. Besides, chitin, cellulose and polysaccharides are the most abundant natural biomaterials have been widely used by human. Elucidating the precise control of the multi-scale structure and dynamics in biomacromolecules, and furthermore, developing biopolymer materials with high performance through multi-scale biomimetic methods, and achieving the high-performance for traditional synthetic polymers are important research topics in polymer science. In this project, multi-scale solid-state NMR in combination with other characterization techniques will be adopted to reveal the micro-phase separation structure and interface in high-performance natural biomaterials, the hydrogen bond interaction between water and biomacromolecules, the complex chain motion of the biomacromolecules, evolution of multi-scale structure and dynamics during the stretching process as well as its influence on the mechanical properties in different length and time scales, thus to establish the in-depth understanding of the structure-property relationships of high-performance biomaterials. On the basis of the above work and through multi-scale biomimetic molecular design, we will prepare a series of high-performance biomimetic polymer materials based on biopolymers and synthetic polymer with high density of hydrogen bonds, such as chitosan and multi-block polyurethanes. Our work will promote the fundamental research and industrial applications of high-performance biopolymer and polymer materials of our country.