纤维素氢键解离和重构是一个世界性难题。本项目拟系统开展纤维素与深共融溶剂（deep eutectic solvents, DESs）分子间相互作用研究。通过红外光谱（FTIR）、核磁共振（NMR）、石英微晶天平（QCM）、多参数表面等离子共振（MP-SPR）等方法，研究DESs体系中的氢键给体和受体之间和相互作用及其影响因素。在纤维素聚集态结构调控的基础上，研究纤维素与DESs体系分子间的相互作用，探讨DESs体系中氢键给体和受体组分的化学结构、配比、共溶剂以及纤维素聚集态结构和外部条件（如温度和pH值等）对纤维素与DESs之间相互作用的影响，并通过结构和组成优化制备新型的纤维素溶剂或溶胀剂体系。通过本项目的实施，可以为阐明纤维素的氢键解离机制提供科学依据，为纤维素新溶剂体系的设计提供理论指导。本研究工作对纤维素这一丰富的可再生资源的有效利用具有重要的意义。

In order to clarify the broken mechanism of the hydrogen bonds, one of the undissolved problems, of cellulose, we will investigate the interaction between cellulose and the molecules of deep eutectic solvents (DESs) in details by using Fourier transform infrared (FTIR), nuclear magnetic resonance (NMR), quartz crystal microbalance (QCM), multi-parametric surface Plasmon resonance (MP-SPR), etc.. The interactions among the hydrogen-bond donors (HBDs) and hydrogen-bond acceptors (HBAs) of DESs and their correlations with the chemical structure and components of the HBDs and HBAs will first investigated. Based the preparation of cellulose samples with different structure in condensed state, the interactions between cellulose and DESs and their correlation with the chemical structure and composition of the HBDs and HBAs of DESs, the co-solvents, the structure of cellulose in condensed state, and the environmental conditions (e.g. temperature, etc.) will be investigated and discussed. New cellulose solvents or swelling agents will be designed by the optimization of the chemical structure and components of the DESs. The research in this project will provide the scientific supports for the clarifying the broken mechanism of cellulose hydrogen bonding networks and the theoretical background in the design of new cellulose solvent systems. The research of this project is very important to support the efficient usage of the abundant and renewable cellulose resources.