以石墨烯氧化物为前驱物、环糊精衍生物为功能分子，采用非共价功能化方法制备环糊精非共价功能化石墨烯。利用环糊精独特的"内疏水外亲水" 结构特点和分子识别性能，赋予石墨烯在水溶液中优良的分散性能和分子识别能力；基于非共价功能化特点，在充分体现石墨烯独特的单原子层二维平面结构的同时保留其结构的完整性及其所具有的独特的物理化学性质（如高电子输运速度、大比表面积、高电化学活性），以满足电化学传感的需求；此外，基于铂等贵金属纳米颗粒优良的电催化性能，发展贵金属纳米颗粒-环糊精共功能化石墨烯，进一步改善功能化石墨烯的电化学催化性能。以与生命活动相关的小分子、环境污染物和生物分子为研究对象，发展具有高选择性、高灵敏度、响应速度快、测量范围宽等特点的石墨烯基电化学传感器。本项目所开展的石墨烯环糊精非共价功能化及其电化学传感研究，在环境污染物监测、疾病早期预警和药物研究等方面具有广阔的应用前景。

Taking graphene oxide as precursor of graphene, cyclodextrin derivates as functional molecules, cyclodextrin-functionalized graphene was prepared by the non-covalent functionalization method. Based on the special structure (a hydrophobic inner cavity and a hydrophilic outer surface) and molecule recognition property of cyclodextrin, the functionalization of graphene with cyclodextrin will make graphene has excellent dispersibility in aqueous solution and molecule recognition ability. Also, based on the characteristics of non-covalent functionalization,the functionalized graphene will retain and show special physicochemical properties (such as high electron transfer rate, large specific surface area and high electrochemical activity) of perfect, two-dimensional and monolayer structure. These are the desirable properties of the excellent sensing material in electrochemical sensors. Additionally, based on the excellent electrocatalytic properties of noble metal nanoparticles (such as platinum nanoparticles), the co-functionalization of graphene with noble metal nanoparticles and cyclodextrin was carried out to further improve the electrocatalytic properties of the cyclodextrin-functioalized graphene.Tkaing the life-related small molecules,environmental pollutants and biomolecules as the targets,the graphene-based electrochemical sensors with excellent properties (such as good selectivity, high sensitivity, fast response and wide response range) were developed. The obtained results will have promising applications in the monitoring of environmental pollutants, forewarning of disease at the beginning and medicine study.