实现人体高效、安全的外科手术是医疗人员与科技人员共同追求的目标。1.94um波段的激光位于OH-强烈的吸收窗口，高强度的热效应可使人体组织产生凝固、碳化或汽化效应，因此可应用于人体组织的凝固、止血和高效率切除。本项目基于此需求，在前期研究工作基础上，提出发展基于人眼安全的Tm3+:Ho3+共掺光纤激光手术刀。以MCVD车床的“湿法”在线掺杂技术和光纤预制棒侧向开槽技术，制作高浓度光敏Er3+:Yb3+共掺、Tm3+:Ho3+共掺偏振保持光纤、Tm3+:Ho3+共掺偏振保持双包层光纤。基于种子光放大技术和特种光纤器件制作技术，通过所开发出的激光刀头的光电系统与软件控制系统实现输出模式的连续、脉冲可切换，输出功率大小与焦点位置可调的Tm3+:Ho3+共掺光纤激光手术刀。为人体软组织切割、视网膜缝合、肌体内部病变组织的非接触切除等开辟了一条全新的途径，为促进外科手术的技术进步奠定了坚实的基础。

The approaches to achieve efficient and high-safety surgery have always been the research aim of medical staffs and technicists. Due to the strong absorption of OH- at 1.94 um, the generated high thermal effect can induce solidification, carbonization and vaporization on human tissue. Thus laser at 1.94 um can be applied on tissue coagulation, hemostasis and excision. In this program, according to the previous work, an eye-safety Tm3+:Ho3+ co-doped fiber laser scalpel is proposed to cater to the demand of high-safety surgery. Utilizing MCVD-based special solution doping technique and side-groove method, photosensitive high-doped Er3+:Yb3+ fiber, Tm3+:Ho3+ co-doped polarization-maintaining fiber and Tm3+:Ho3+ co-doped double clad fiber are fabricated. The Tm3+:Ho3+ co-doped fiber laser scalpel using MOPA and special fiber components can operate at either continue-wave mode or pulse mode. Meanwhile, laser output power and focus position can be adjusted by precise optic-electro-mechanical system. It has potential application in human soft tissue cutting, retina suture and diseased tissue resection.