接枝聚合物纳米粒子集合了无机纳米粒子独有的光、电、磁、激发子、表面等离子体等特性与聚合物结构易调控、材料易加工等特点，在目前自组装研究领域中占有特殊重要的地位。然而由于该体系的自组装过程涉及微观及介观尺度上复杂热力学性质与动力学过程，因此对其自组装机理的深入认识与结构和性能的精确调控仍远未尽人意。本项目将理论模拟与实验研究有机结合，解决接枝聚合物纳米粒子自组装研究中面临的重要科学问题，包括：（1）发展有效表征表面接枝聚合物链微观性质的方法，明确接枝聚合物纳米粒子表面的微观特性；（2）发展表征及调控接枝聚合物纳米粒子之间有效相互作用的手段；（3）明确接枝聚合物纳米粒子自组装过程中的热力学和动力学因素，从而明晰接枝聚合物纳米粒子自组装的机理，建议新实验、推动新应用。力争取得2-3项在学术界有影响的重要成果，在国际上占有重要一席之地。

Polymer-tethered nanoparticles are extremely important building-blocks in self-assembly, since they incorporate unique properties (such as optic, electric, magnetic, and plasmonic) of inorganic nanoparticles with excellent mechanical properties of organic polymers in one system. But the full understanding of the self-assembly mechanism and the fine-tuning of the structure and property are far from satisfactory, due to the multiscale nature of thermodynamics and dynamics in the self-assembly process of polymer-tethered nanoparticles. In this study, we will combine theoretical/computational and experimental tools and develop new techniques to achieve: (1) Develop new characterization methods to make clear microscopic structure and property of polymer chains tethered on the nanoparticle surface; (2) Develop efficient theoretical/computational and experimental tools that can manifest the physical nature of effective interaction between polymer-tethered nanoparticles; and (3) Clarify the thermodynamic and dynamic influences in the self-assembly process of polymer-tethered nanoparticles. By the successful fulfillment of this study, we will deepen the understanding of self-assembly mechanism of polymer-tethered nanoparticles in different thermodynamic conditions, and put forward new experiments and applications.