近年来，随着LED照明的普及以及光的非视觉生物效应研究的迅速发展，具有健康效应、特别是人体生物钟节律干预效应的室内照明逐渐成为研究热点。本课题将光生物学最新研究成果应用于照明技术，在传统室内照明研究关注于光谱的显色性、色温、效率、色彩准确性等指标的基础上，将光谱的“节律作用因子”（circadian action factor）作为一个新的指标进行优化。本课题从理论上计算照明光谱的“节律作用因子”可调控范围，及其受重要照明指标的制约关系；系统性地提出基于不同需求（如卧室休息空间、办公室工作空间等）、不同时段优化的照明光谱；并制备相应的LED照明光源，开展人居环境光健康量化研究，建立室内照明“节律照度”（circadian illuminance）值和实际人体节律干预效应的关联。本研究可为健康照明技术及人居环境光健康研究提供重要的理论支持，对室内人群生活质量和健康状况的改善有重要的应用价值。

In recently years, as LED lighting becomes popular and research on non-visual biological effects of lighting develops rapidly, the indoor lighting with health effects (especially on the intervention of human circadian rhythms) gradually becomes a hot research topic. In this study, we apply the latest research achievements of Photobiology into lighting technology. Beyond the traditional lighting research that focus on lighting spectra’s color rendering index (CRI), color temperature (CT), luminous efficacy of radiation (LER), and color accuracy, we adopt “circadian action factor” (CAF) of lighting spectra as another important parameter for optimization. This study calculate the theoretical range of CAF, and its trade-offs with other important lighting parameters. We further systematically propose optimized lighting spectra for various indoor lighting applications. For example, optimized spectra for bedroom lighting, for office lighting, and for various times (morning, daytime, and evening) during the day. We then develop LED sources with the corresponding optimized spectra, and carry out quantitative research on “health lighting for living environment”, establish the correlation between “circadian illuminance” quantity and actual intervention effect of human circadian rhythm. This study could provide important theoretical support for health lighting technology and research on "healthy lighting for living environment", help improve people's life quality and health condition.