木质纤维中木质素-碳水化合物复合体（LCC）具有独特的抗氧化、抗菌活性和细胞毒性功能，是一种有重要应用前景的生物活性物质。传统的LCC制备提取技术会导致其化学结构改变及生物活性的丧失。LiCl/DMSO木质纤维全溶体系具有绿色、环保，且对木质纤维各组分的化学结构友好等特点，对提取原本LCC卓有成效。轻度球磨预处理的麦草纤维经LiCl/DMSO全溶处理，通过开展“液-液提取”并组合多种分级提取方法，定向分离出麦草中具有不同酸碱度、分子量、以及木质素/碳水化合物组成的LCC等方面的系统研究，掌握全溶体系下LCC的提取、分离及提纯新技术；揭示麦草在LiCl/DMSO全溶体系中的溶解规律与特性；研究分析各级分LCC的抗氧化、抗菌活性和细胞毒性，确定药效结构，最终建立LCC的生物活性构效关系，为开发与利用禾本科原料LCC生物活性物质提供理论依据。

The lignin-carbohydrate complex (LCC) in lignocellulose has unique antioxidant, anti-microbial activities and low cytotoxicity. It is a kind of bioactive substances with great application potential. The traditional method for LCC extraction may cause the chemical structure alternation and the biological activity loss. LiCl/DMSO solution is an environmental solvent for dissolving lignocellulose, and also has great effect on the extraction of proto-LCC. Wheat straw with slightly ball-milling will be dissolved in LiCl/DMSO, then extract the LCC which has different acidic groups, molecular, and the ratio of lignin to carbohydrate. Then a novel technology of LCC extraction, separation and purification will be presented, and the specific properties of lignocellulose dissolution of wheat straw in LiCl/DMSO will be in-depth reveled. Finally, the bioactive structure-activity relationship of isolated LCC is going to be established by discussing the antioxidant, anti-microbial activities and cytotoxicity, as well as elucidating its pharmacophore. All these research will make contribution to complementing the theoretical foundation for efficient utilization of bio-activity LCC of gramineae lignocellulose