时空编码谱技术沿着空间维激发编码，并行接收解码，只要单次扫描即可获得一张二维谱。灵敏度低、间接维分辨率低、谱宽受限制约时空编码谱技术应用于低浓度复杂样品检测。带偶合网络的新型二维J分解谱方法能够单独提取感兴趣自旋的偶合网络。为此本课题拟根据时空编码k空间、反k空间、频率域信号特点，建立合理数理模型，设计新型时空编码方法:(1)采用直接维非均匀采样和稀疏重建方法提高时空编码谱灵敏度并解决谱宽受限问题；(2)利用相位匹配方法消除采样信号移位、倾斜等问题；(3)在频率域利用信号处理方法提高分辨率。同时，本课题拟结合傅立叶变换矩阵调制多色脉冲、选择性COSY、纯化学位移模块等谱方法提取多个感兴趣质子偶合网络显示在对应二维谱中，其中一维仅显示与感兴趣自旋相偶合核的化学位移，另一维显示偶合常数，谱峰为吸收线型。超快速实现高灵敏度高分辨率化学生物样品组成和结构分析，拓展NMR向更深层次更广泛应用。

Based on parallel excitation coding, parallel reception and decoding acquisition methods, a two-dimensional spectrum can be obtained within a single scan by the ultrafast spatiotemporal technology. This ultrafast technique is limited by the low sensitivity, the low resolution along the indirect dimension, and the spectral width compromised along the indirect and direct dimensions. The coupling network of a specific proton can be extracted from the crowded spectra by the novel two dimensional J-resolved spectral technique. We will analysis the characteristics of the signal in the k-space, inverse k-space and frequency domain, built a proper mathematical model, and design novel spatiotemporal encoding technology: (1) the non-uniform sampling and the sparse construction algorithm along the direct dimension; (2) phase-match and correction; (3) signal processing in the frequency domain. We will focus on designing polychromatic pulses encoded by the Fourier matrix and writing the corresponding decoding algorithm, introducing selective COSY and pure shift element. Therefore the pure chemical shift of spins coupled to the interested spin and the coupling constant are shown along the direct and indirect dimensions of the novel 2D J-resolved spectra with absorbing peaks. High-sensitivity and high-resolution analyses of chemical components and structures were realized.