在碱的存在下，铜离子与2,2,6,6-四甲基哌啶氮氧化物（TEMPO）的催化体系（Cu/TEMPO催化体系）能够高效催化醇的氧化反应。对于非均相Cu/TEMPO催化体系，制备高性能催化剂的关键是实现对三个组分（铜离子、TEMPO、碱）的相对浓度以及相互作用的精准调控，但是现有制备方法难以达到。本项目提出了一种非均相Cu/TEMPO催化体系的可控制备方法：以苯乙烯为主单体制备分别含有铜离子、TEMPO、碱的三类共聚物，基于纳米沉淀技术实现非均相Cu/TEMPO催化剂的可控制备。其中，三个组分的相对浓度可通过共聚物的投料比精准控制，同时调节共聚物的组成可控制三个组分的固相浓度，起到调控三个组分相互作用的效果。在制备过程中，共聚物链段的柔性（弯曲、缠结）促进了不同共聚物之间的接触，有利于相互作用的形成。本项目旨在阐明非均相Cu/TEMPO催化剂的结构与催化性能的关系，为其合理设计提供参考。

Copper ions and (2,2,6,6-tetramethylpiperidin-1-yl)oxyl (TEMPO) work cooperatively (Cu/TEMPO catalysts) to catalyze the aerobic oxidation of alcohols in the presence of bases. To obtain an efficient, heterogeneous Cu/TEMPO catalyst, the key is the precise control of the relative concentrations and the interactions between each component. To the best of our knowledge, current approaches for the synthesis of multi-component and heterogeneous catalysts are relatively complex and unpredictable. Here, we propose a new approach for the controllable synthesis of heterogeneous Cu/TEMPO catalysts. Three types of copolymers containing copper ion, TEMPO, and base, respectively, will be synthesized by using styrene as the main monomer. Heterogeneous Cu/TEMPO catalysts will be synthesized by using nanoprecipitation technique. The relative concentrations between each component shall be tailored by varying the feed ratio of copolymers, and the interactions between each component shall be tailored by varying the solid concentrations of each component, which depend on the compositions of copolymers. We believe the bending and entanglement of polymer chains can effectively facilitate the formation of active sites. We aim to clarify the relationships between structures and catalytic properties of heterogeneous Cu/TEMPO catalysts, which can promote the rational design of catalysts.