纳滤/反渗透高压膜工艺是对城市污水进行再生、制备高品质再生水的重要技术手段，然而膜污染是制约系统稳定运行的关键。针对城市污水处理厂二级出水复杂体系中无机-有机-生物耦合膜污染机制不清，膜污染控制对策不力的现状，深入开展相关研究意义重大。本研究将基于先进的物理、化学以及生物学分析手段，以反渗透膜工艺为例，主要研究反渗透高压膜污染动态发展特征，识别无机污染、有机污染以及生物污染对膜过滤阻力的贡献；基于分子水平，深入解析无机-有机-生物之间的膜污染耦合效应与动态作用机制，揭示无机-有机膜污染耦合效应高的关键无机离子和有机组份、生物污染诱发潜势高的关键无机和有机因子；探索这些关键因子的去除原理和方法，建立基于关键因子调控的高压膜工艺膜污染控制新策略。研究结果对于从理论和技术上支持反渗透等高压膜工艺在城市污水再生回用中的稳定运行具有重要意义。

High pressure membrane filtration processes, such as nano-filtration and reverse osmosis (RO), are important technologies for producing the reclaimed high quality water from municipal wastewater, whereas the membrane fouling has always been the bottleneck of the stable operation of such systems. Up to date, it is vague that the mechanisms of synergistic fouling by inorganic, organic and biological foulants, and improvement is urgently required in current fouling suppression techniques. Thus, it is of great significance to conduct deep relevant investigations on such fields. In this study, RO membrane will be adopted, its dynamic fouling development will be characterized, and the respective contributions of inorganic, organic and biological fouling to the filtration resistance will be identified using advanced physico-chemical and biological analysis measures. Furthermore, the synergistic effect and dynamic mechanisms of interaction among inorganic, organic and biological fouling will be dissected at the molecular level, to reveal the key inorganic ions and organic components causing high synergistic effect of organic-inorganic fouling as well as such key factors with high potential to induce biological fouling. Besides, principles and methods will be investigated to remove those key factors, and new strategies for fouling suppression will be established based on the regulation of relevant key factors. The outcome of this study would be expected to offer significant support both theoretically and technically to the stable operation of high pressure membrane processes such as RO in reclamation and reuse of municipal wastewater.