Sr同位素（87Sr/86Sr）和Ca同位素（δ44/40Ca）是重要的地球化学指标，能够有效地示踪源区和过程，二者的结合在地球科学和环境科学等领域具有极大的应用潜力。广泛应用的重要前提是获得高精度的Sr-Ca同位素数据。热电离质谱仪（TIMS）是高精度分析地质样品中Sr-Ca同位素组成的经典方法。然而，Sr-Ca样品需要经过多次化学分离，并分别装载上机测试。因此，样品分析效率很低。本研究拟通过开发单柱化学分离流程和建立新型的样品装载技术，针对性地解决制约Sr-Ca同位素分离和测试效率的瓶颈，同时引入快速自动分离系统，最大程度提高样品处理效率，最终建立TIMS快速准确测定地质样品Sr-Ca同位素的分析方法，为高精度Sr-Ca同位素更广泛的地质应用提供技术支撑。

The Sr isotope (87Sr/86Sr) and Ca isotope (δ44/40Ca) are very important geochemical tracers for sources and processes, and the combination of both isotopic systems have great potential in the fields of geology and environment sciences. Thermal ionization mass spectrometry (TIMS) offers the excellent precision and accuracy of the Sr and Ca isotopic ratio analyses for geological samples. However, the sample should be purified several times and then loaded separately for high precision Sr and Ca isotopic ratios measured by TIMS. Thus, the sample throughput of this method is very low. The aim of this project is to develop a single-step chemical separation method to simplify the purification procedure. What’s more, the fully-automated chromatography system will be employed to improve the sample throughput and reduce the labor costs. We will also develop a novel loading protocol, allowing the Sr and Ca sample load simultaneously, in order to improve analytical efficiency. Ultimately, the rapid and high precise method for Sr and Ca isotopic analyses by TIMS will be established for a wide range of geologic applications.