耳穴超声调控节律失调与睡眠障碍的方法研究

睡眠障碍会严重影响人的身心健康和生活质量，睡眠改善的方法研究是医学超声领域的研究前沿和热点之一。本项目提出利用超声刺激耳穴的方法进行改善睡眠质量的研究。针对节律失调和心理因素造成的睡眠障碍患者，采用超声调控和虚假辐射的方式进行研究，揭示超声刺激下自主神经系统变化规律以及心、肺系统与自主神经系统间的协同工作、相互影响及反馈机制；阐明超声调控的生理机理，为预防和改善睡眠障碍提供理论依据；构建基于机器学习的自动睡眠检测系统，实现睡眠质量评估的准确性与简单性；优化超声作用参数，设计便于挂戴的耳罩式超声辐射系统；将超声调控与传统针灸进行对比，并将其试应用于临床。本项目研究对于发展新的研究方法、拓宽超声医学信号的研究思路具有重要的学术意义；对辅助临床治疗实际睡眠障碍问题、提高人民生活质量具有非常重要的现实意义。

Sleep disorder can seriously affect human physical and mental health, and reduce life quality. The method research on improving sleep is research frontier and hot topic in the field of medical ultrasound. In this project, the method that using ultrasound stimulating the human auricular acupoints was put forward. For patients with sleep disorders caused by rhythm disorder and psychological factors, using the methods of ultrasonic regulation and false radiation to reveal the change rule of autonomic nervous system. Clarify the physiological mechanism of ultrasonic regulation and provide theoretical basis for preventing and improving sleep disorder by researching the cooperative work, mutual influence and feedback mechanism among the heart system, lung system and autonomic nervous system. The automatic sleep detection system based on machine learning is built in order to realize the sleep quality evaluation accurately. According to the structure of the ear and the characteristic of the acupoint position, the earmuff type ultrasonic radiation system is designed and the ultrasonic radiation parameters are optimized in combination with the ultrasonic regulation mechanism. At the same time, compared with traditional acupuncture, ultrasound regulation method is applied to clinic tentatively. This project has important academic significance for developing new research methods and broadening the research ideas of ultrasound medical signals. Meanwhile, this research has very important practical significance for assisting clinical treatment and improving human life quality.