航天飞行后可引起航天员心血管功能失调，主要表现为立位耐力不良，甚至晕厥，给航天员健康造成巨大威胁。目前国内外主要采取防护设备和对抗动作等措施来预防立位耐力不良，但这些措施并未根本解决其问题，因此，如何防治飞行后立位耐力不良是国内外航空医学界最为关注的重要问题。我们前期研究首次证实我国传统医学电针可以改善心血管调节功能，增强心脏泵血能力，提高交感神经的兴奋性，增加脑血流量；同时还可提高机体对抗缺血的能力。因此，我们推测：电针刺激有可能通过调节心脑血管功能对失重后立位耐力不良起到防护作用。为证实此假说，本项目以心脑血管功能为切入点，选择尾悬吊法模型和人体头低位卧床试验模拟失重效应，综合运用多种重力生理学技术，探讨电针对模拟失重后立位耐力不良防护的作用并确定其最佳刺激参数。本研究结果将有助于深化失重后立位耐力不良防护方案的制定，为失重致航天员立位耐力不良的防护提供新的思路和理论依据。

Individuals exposed to extended periods of microgravity during spaceflight often suffer from symptoms of cardiovascular. The cardiovascular dysfunctions include increased incidence of orthostatic intolerance (OI) and frank syncope. Cardiovascular dysfunction is severe threat to aviation safeties. At present, the preventive methods against OI mainly adopt anti-G suit and adaptive training in pre-flight. Unfortunately, currently available methods against OI do not result sufficient symptomatic improvement. So, it is a so urgent task to explore novel, convenient and effective method against OI. Our previous studies have demonstrated that electroacupuncture (EA) is highly effective in activating peripheral sympathetic nervous system an improving cardiac and brain function. We hypothesis that EA could ameliorate OI after weightlessness by improving cardiovascular function. Based on this discovery, the present study is to explore EA against OI by a combination of using the Hind-limb unloading rodent model and gravitational physiological techniques. Furthermore, we further test effect of EA against OI and optimal stimulation parameters in head-down tilt bed rest in health volunteers. The studies could provide novel insight and theoretical evidence for establishing our nation's exercise program in manned spaceflight.