本研究选择宁夏地区回汉族儿童青少年作为研究对象，了解宁夏回汉族儿童青少年超重肥胖、高血压、高血脂、高血糖等心血管疾病危险因素流行现状，拟采用混合效应模型构建儿童期BMI、SBP、DBP、脂代谢异常等各指标的轨迹曲线方程，以PWV、cIMT、LVMI及RWT在不同性别的P75作为诊断亚临床CVD的切点，诊断高PWV（含同性别同年龄P75）、高cIMT（含同性别同年龄P75）、高LVMI（含同性别同年龄P75）及高RWT（含同性别同年龄P75），进一步根据高LVMI及高RWT评价左心室几何构型（Left ventricular geometry,LVG），分析不同肥胖类型、肥胖程度、血压和血脂水平下心血管结构和功能指标的改变，从而评价儿童青少年拥有不同程度心血管疾病危险因素及交互作用对心脏结构和功能的影响，为降低患心血管疾病的风险提供一定的科学依据。

Abstract By using field investigation, laboratory test and clinical examination to understand the epidemic situation of cardiovascular disease associated risk factors such as overweight and obesity, hypertension, hyperlipidemia and hyperglycemia in children and adolescents among different nationalities in Ningxia. A hybrid effect model is proposed to construct the trajectory curve equation of BMI, SBP, DBP and abnormality of lipid metabolism in childhood. The pulse wave velocity, carotid intima media thickness, left ventricular mass index and relative wall thickness were used in the P75 of the same sex as the diagnosis of subclinical CVD point. High PWV, high cIMT, high LVMI and high RWT, all the indexes above with the same sex and age P75, further evaluation of left ventricular geometry based on high LVMI and high RWT. The analysis of the changeable of structure and function of cardiac in different types and degrees of obesity, blood pressure and lipid levels, to evaluate the effect of cardiovascular risk factors in children and adolescents with different levels and their interaction on cardiac structure and function, provide a scientific basis for reducing the risk of cardiovascular disease.