目前开发的生物医用多孔钛合金的孔结构与人体骨质特征存在偏差，且常用合金中V、Al元素的释放对人体产生毒副作用，开发具有更优生物相容性和骨骼匹配度的多孔钛合金是目前生物医用钛合金发展的主要方向。本项目采用选区激光熔化技术制备连续密度梯度多孔Ti15Mo合金，调控与优化多孔合金的孔结构和微观组织；研究连续密度梯度多孔Ti15Mo合金在循环应力、模拟人体体液交互作用下的腐蚀疲劳行为；探究材料在整体循环变形过程中各单元胞协调变形、孔棱裂纹萌生与扩展的规律，揭示连续密度梯度多孔Ti15Mo合金的腐蚀疲劳机理；研究微观结构演化与材料性能变化之间的形性演变关联，发展连续密度梯度多孔材料腐蚀疲劳寿命预测模型。研究成果将为梯度多孔钛合金的设计制备及其在生物医用领域中的应用提供科学支持。

At present, some characteristic devitations exist between the biomedical porous titanium alloys and human nature bone. Furthermore, the releasing of cytotoxic Al or V ions from the Ti alloy implant into human body fluid might cause long-term potential biological problems. Currently the development of novel porous titanium alloys with better biological and mechanical properties becomes the main research point in the biomedical materials field. In this project, continuous graded porous Ti15Mo alloys will be prepared by selective laser melting(SLM) technology, the geometrical structure and microstructure of the porous alloy will be designed and optimized. The corrosion fatigue behavior of the porous titanium alloy will be investigated with the synthetic effects of cyclic stress and simulated body fluid. The laws of compatible deformation of unit cell in the porous alloy and crack initiation and propagation on the strut will be explored during cyclic deformation, aiming to reveal corrosion fatigue mechanism of continuous graded porous Ti15Mo alloys. Furthermore, the relationship between the microsturcture evolution and properties of porous titanium alloys will be established. Finally the corrosion fatigue life prediction model of continuous density gradient porous material will be developed. The research results will provide a scientific basis for the design of graded porous titanium alloy and its application in biomedical field.