全氟化合物(PFCs)作为一类全球关注的新型污染物，具有疏水和疏油的特性，与传统疏水性有机污染物存在显著差异，但目前有关PFCs的研究主要集中在分布、来源、长距离传输和生物毒性方面，有关其生物富集作用的研究相当欠缺，有关水环境中有机质对其生物有效性的影响研究几乎为空白。本项目将水体环境学、环境化学、环境地学和环境生物学等方法相结合，研究典型PFCs在底栖和浮游动物中的生物富集作用；深入剖析沉积相和水相中不同来源和组成有机质(包括黑炭、腐殖质和非腐殖质物质)对PFCs生物富集作用的影响程度及影响机理；鉴于PFCs易与蛋白质相结合的特性，着重研究比持久性有机污染物PFCs含量高出数个数量级的耗氧性有机污染物蛋白质对PFCs生物有效性的影响；探讨不同pH和离子强度条件下有机质的影响；揭示影响PFCs生物富集作用的关键有机质组成，进一步深化PFCs的水环境行为研究，为其生态风险评价提供科学依据。

Known as a class of emerging organic pollutants of global concern, perfluorinated compounds (PFCs) exhibit unique hydrophobic and oleophobic properties that are notably different from the traditional organic counterparts. Previous studies about PFCs focused mainly on distribution, source, long-distance transport and biological toxicity. However, study on the bioaccumulation of PFCs is surprisingly scant, and the current understanding of the influence of organic matter on the bioavailability of PFCs in aquatic environment remains almost blank. In this project, various useful methods in aquatic environmental science, environmental chemistry, environmental geosciences as well as environmental biology will be employed as a whole to study the bioaccumulation of typical PFCs in zoobenthos and zooplankton. Specifically, we will conduct in-depth analyses of the extent as well as the mechanisms of the influences of organic matters, in both sedimentary and water phases with different sources and compositions (i.e. black carbon, humus and non-humic substances), on the bioaccumulation of PFCs. Given the fact that PFCs can easily bind to proteins, our study will pay great attention to the influence that the proteins, one kind of oxygen-consuming organic pollutant with a content several orders of magnitude higher than PFCs, have on the bioavailability of PFCs. The effects of organic matter on PFCs bioaccumulation under different pH and ionic strength conditions will also be studied. Furthermore, we will reveal the key components of organic matter that influence the bioaccumulation of PFCs most on the basis of experimental evidences, in an attempt to further promote the research on the behavior of PFCs in aquatic environment as well as to provide scientific basis for the ecological risk assessment of PFCs.