纳米材料凭借独特的理化性质，已成为提升普通传感器性能的利器。如何构造合理的敏感单元结构，突破纳-微集成制造难题，建立集成检测微系统，是推进纳电极传感器走向实际应用的重要技术前提。桥接式纳米结构敏感单元能够通过桥接在测试电极两端的有限数量纳米材料实现目标物超高灵敏度检测，目前已成为纳电极传感器首选的敏感单元结构。然而，传统加工方法无法有效解决桥接纳米材料与金属电极界面弱结合的问题，更不能满足其批量化制备和集成化发展的需求，极大的制约了其集成检测系统的发展。本项目基于纳米材料/聚合物复合物薄膜，巧妙组合微加工工艺构造纳-微跨尺度集成工艺路线，在此基础上提出一种集采样、制样、检测及后处理功能于一体的桥接式纳电极集成检测微系统设计。项目将建立针对桥接式纳米结构单元制备的纳米材料分散操控和可控植入的理论设计方法，开展桥接式纳米结构单元集成制备和敏感机制功能化集成系统研究，并通过原型器件验证设计思想。

Nanomaterials can enhance ordinary sensor performance with unique physical and chemical properties. How to construct a reasonably sensitive cell structure, sovling nano-micro integrated manufacturing problems and establishing integrated detection micro-system are important technical prerequisites for advancing the nanoelectrodes sensor toward practical application. Ultra-high-sensitivity detection of the target material can be achieved by limited nanomaterial between the two test electrodes in bridge-nanostructures sensitive unit which has become the preferred nanoelectrodes sensor sensitive cell structure. However, the traditional methods can not effectively avoid weak bonding between the bridge nanomaterials and metal electrode. In addition, these methods can not meet the needs of the bulk of the preparation and the integrated development, which greatly restricts the development of the integrated detection system. In the present program, a nano-electrodes detection microsystem has been proposed based on a clever combination of nanomaterial/polymer composite film and nano-micro processing technology. This design includes sampling, sample preparation, detection and post-processing functionality. The theoretical design method will be constructed for control the dispersed nanomaterials and implanting process of the bridged nanostructure unit. How to integrate the bridged nanostructure unit and detection micro system will be developed based on the sensitive mechanism of the unit. Finally, the fabricated detection system will be tested and characterized for evaluating its overall performance.