基于金属有机框架和有机共晶策略调控2/2,6-芳基取代的BODIPYs类材料发光性能的研究

本项目旨在通过金属有机框架(MOFs)和有机共晶策略调控2/2,6-芳基取代BODIPYs的固态发光性能，利用晶体材料有序的结构特点来调节其分子构型和排列模式，有机分子的构型和排列方式直接影响着材料的发光行为，并且受金属重原子效应、π···π堆积、J-聚集效应等协同作用影响，可实现构筑丰富的可调谐激发/发射波长材料的目的。BODIPY作为一种明星分子，被广泛地应用于生物传感和生物成像。然而，由于大多数BODIPYs具有聚集诱导猝灭现象，关于BODIPYs的固态发光研究较少，我们课题组利用2/2,6-芳基取代的BODIPYs荧光染料，首次实现了从绿光到近红外光的多重荧光发射，这种独特的发光特性驱使我们进一步探索这类分子的发光行为。本项目中MOFs材料调节BODIPY分子排列构型的策略不仅提供了一种新的调控BODIPYs荧光的方法，而且其多孔、高度有序的结构特点也将拓展该类材料的应用。

This proposal aims to tune the solid-state luminescent behavior of 2/2,6-aryl substituted BODIPYs molecules by means of metal-organic frameworks (MOFs) and organic cocrystal strategies. The ordered structure of crystal materials can help to adjust the molecular configuration and arrangement pattern of BODIPYs molecules. The configuration and arrangement of organic molecules directly affect the luminescence behavior of materials. In addition, the synergistic effects of heavy metal effect, π··· π packing interactions and J-aggregation can also alter the luminescent behavior. Therefore, the implementation of MOFs and organic cocrystals strategies is possible to achieve the purpose of constructing the luminescent materials with tunable excitation/emission wavelengths. BODIPY, as a star molecule, has been widely used in biosensors and bioimaging due to its excellent luminescent properties in solution. However, due to the aggregation-caused quenching phenomenon of most BODIPYs, there are few studies on the solid-solid luminescence of BODIPYs materials. Recently, our group have reported a series of 2/2,6-aryl substituted BODIPYs fluorescent dyes which firstly achieve the multiple fluorescence emission from green to near-infrared emission. The unique luminescent properties drive us to further study the luminescent behavior of this kind of molecules. In this project, the strategy of MOFs and cocrystal materials to adjust BODIPYs molecular configuration not only provides a new method to adjust fluorescence of BODIPYs molecules, but also the porous and highly ordered structure of MOFs will further expand the application of BODIPYs materials.