本项目将采用多模态信息融合的新技术和新方法研究注意定向可塑性，针对孤独感人群设计认知实验任务进行注意定向可塑性训练，对孤独感的动态脑网络（功能环路和结构环路，并结合EEG）进行深入细致的研究,在认知水平和神经水平上揭示孤独感的神经机制，推动神经成像技术和具体的认知科学问题结合的研究。本项目的研究成果将为临床注意定向所引起的认知障碍治疗提供神经影像学依据。同时，由于目前对于孤独感的研究多集中在青少年和老年，本项目针对青年可进一步扩充孤独感研究的人群范围。因此，采用多模态技术研究注意定向可塑性的功能和结构环路进而揭示其产生机制，对科学研究和临床应用具有重大意义。

Using new technology and new method, multimodal information fusion is adopted in this project to research the attentional orienting plasticity. Cognitive experiment task training is designed for the loneliness. The dynamic brain networks (functional and structural circuites with EEG) of loneliness were deeply investigated to reveal the neural mechanisms of loneliness in the cognitive and neural levels and improve the association between neural imageing technologies and specific cognitive science. Research results of this project would promote the clinical therapy for cognitive deficiency of attentional orienting. Additionally, unlike the current lonely studies focus on the adolescents and the old, the project aims at the youth to extend the range of reaserch objects.Therefore, it is important to study the functional and structural circuits of loneliness in the youth by using multimodal technologies on the science researches and clinical applications.