本研究拟在复杂自适应系统（complex adaptive system，CAS）思想的指导下综合运用社会学流行病学、组织行为学、风险管理学等学科的相关理论与研究方法，对医院系统运作流程进行解构、分析。在系统研究国外病人安全文化问卷、量表的基础上，开发适合我国国情的病人安全文化测量工具；通过病人安全态度(attitudes) 调查，了解测量机构的病人安全风气(climate)，从而了解医疗机构的病人安全文化，判断医疗机构病人安全文化总体程度，分析医疗机构的特征、不同工作岗位、不同工作性质调查对象群体之间病人安全文化的差异。在此基础上筛选病人安全文化建设中的重要领域、关键环节、制约因素，了解病人安全文化与医疗结果之间的相关性。同时拟借助Vensim软件系统构建病人安全文化系统动力学模型，用于静态分析和模型模拟，为制定病人干预措施提供理论依据，为理论研究成果转化为现实管理实践提供方法学支持。

This research focuses on medical risk control, patient safety management of the hospital under the guidance of the theories integrated by social epidemiology, organizational behavior, and risk management. To analysis the hospital operation flow system from the perspective of complex adaptive system（CAS）theory. To develop our own patient safety culture (PSC) questionnaire based on systematic analysis of PSC measurement tools abroad. Then using it to evaluate PSC of medical institutions, judge their overall PSC level. To identify focus areas, key points, restricting factors, and correlations between PSC with medical results. At the same time use Vensim software system to construct the PSC dynamics model for static analysis and simulation, to provide the theory basis for patient safety intervention, to provide methodological support for translating research results into practice.