以大环化合物为结构单元构筑交联聚合物，利用大环主体与客体分子的非共价相互作用，探究大环交联聚合物在有机小分子的吸附与分离、气体分离与存储、药物负载与缓释等方面的应用是当今国际前沿研究课题。与传统大环分子相比，分子笼具有更高级的预组织度和永久的空腔结构，在交联聚合物的构筑与应用方面具有更大的优势。因此，本项目首先探索笼状间苯二酚大环芳烃的高效合成方法，研究该类分子笼对多种客体分子的特异性识别行为，阐述其对客体分子的选择性键合原理。进一步利用对苯二甲醛、对苯二硼酸或金属离子等将分子笼交联，构筑系列聚合物材料，探讨该类材料的吸附分离性能与选择性键合之间的关系，继而将其应用于有机污染物的吸附与分离。

It is a frontier research topic to construct macrocyclic crosslinked polymers, and employ host-guest interactions to expand their applications in the fields of adsorption and separation of small molecules, gas separation and storage, drug loading and sustained release. Comparing with conventional macrocycles, caged molecules have better pre-organized structures and permanent pores, which show great advantages in the construction and application of crosslinked polymers. In this project, we intend to initialize with developing an efficient synthetic method for caged resorcinol-based macrocycles, and then investigate the specific recognition behaviors of the molecular cage with a variety of guest molecules. Furthermore, a series of macrocyclic crosslinked polymers will be synthesized by crosslinking the molecular cage with terephthalaldehyde, p-diphenylboronic acid or metal ions. Finally, the molecular cage-based materials will be applied in the area of adsorption & separation of organic pollutants and the relationship between their functions and selective binding properties will be expounded.