光诱导不对称活性超分子聚合体系的设计合成及其手性放大机制研究

手性超分子聚合物和活性超分子聚合均为当前研究中的重要领域，本项目将超分子手性调控与活性超分子聚合进行交叉结合，项目中将设计并合成一系列新型光诱导的不对称活性超分子聚合体系，对单体分子进行表征研究；以圆偏振光照射和手性溶剂中的光异构化反应两种方法对体系开展手性诱导和调控研究，研究光诱导不对称活性超分子聚合过程的热、动力学以及手性传递和放大机制，阐明体系中多重聚集态的相互转化途径与规律，研究并阐明分子单体的化学结构以及圆偏振光等手性因素对于超分子聚合物手性结构的影响规律；探索利用非手性及外消旋单体分子，通过光诱导活性超分子聚合实现单一手性超分子聚合物及手性可控超分子嵌段共聚物的制备。

In current research， both chiral supramolecular polymers and living supramolecular polymerization are important areas. Thus, in this project, the control methods for supramolecular chirality is combined with living supramolecular polymerization. Based on the project, we will design and synthesize a series of new light-induced asymmetrical living supramolecular polymerization systems and the new monomer molecules will be characterized. Two methods to induce the chirality of the system, i.e. irradiation by circularly polarized light and photo-isomerization in chiral solvents, will be applied for the chirality modulation for the system. The thermodynamics, kinetics, and the chiral transfer and amplification mechanisms of the photo-induced asymmetrical supramolecular polymerization process will be investigated. The pathway complexity of for the mutual conversion of the multiple aggregation states in the system will be elucidated. Furthermore, the effect of chemical structure of molecular monomers and the source of chirality, such as circular polarized light etc., on the chiral structure of the supramolecular polymers will be studied and explained. The preparation of homochiral supramolecular polymer and chirality-controllable supramolecular block copolymer by the photo-induced living supramolecular polymerization of achiral or racemic monomeric molecules will be explored.