手性配位空间的构筑及性能研究

手性配位空间材料因其独特的结构和功能，在化学、材料、医药等领域具有非常重要的应用前景。其构筑方法目前还存在着许多亟待解决的重要科学问题，如：单一手性构筑单元的合成问题，手性在空间中的传递问题，手性配位空间与手性分子间的相互作用问题等等。本项目拟围绕这些重大科学问题，提出将手性诱导基元的引入到手性配位空间的构筑中的策略，对无机/有机构筑基元的结构诱导及对配位组装的诱导实现手性在配位空间中的产生和传递，进而实现手性配位空间及相应材料的构筑。基于此，深入研究手性配位空间的构筑规律，探究手性在配位空间中的传递、放大机制，并对所得材料在催化、分离、“晶体海绵”等领域的应用性能进行深入探索。在此基础上进一步通过对手性诱导基元和构筑单元的调整优化，实现材料性能的提升，为手性配位空间的构筑和应用提供新的科学依据和理论指导。

Chiral coordination space materials, owing to their unique structures and properties, have shown important potential applications in many fields. Until now, there are still great challenges in rational construction of these materials. Aiming at these challenges, the concept of “asymmetric induced element” has been drawn into this project, based on which the chiral coordination space could be achieved by utilizing the supramolecular interactions between it and building blocks. In this project, we will explore the construction strategies and the transfer mechanisms of chirality in chiral coordination space. Furthermore, the applications of these materials in catalysis, separation and “crystalline sponge” will also be investigated. On this basis, the asymmetric induced element and building blocks could be further optimized to improve the properties of chiral materials. The achievements of the project will contribute to the construction and applications of chiral coordination space materials in both theoretical and experimental manners.