发展耗散型反应-扩散系统构筑类珍珠层矿物多级有序结构

软体动物壳中的珍珠层是最重要的生物矿化模型体系。由于珍珠层依靠其层状多级有序结构有效地兼顾了强度和断裂韧度，可控制备类珍珠层结构成为了仿生研究的重要目标之一。与实用型仿生方法不同，生物矿化采用了基于自组织矿化的合成策略实现珍珠层生物矿物的可控构筑。本项目计划发展基于耗散型反应-扩散系统可控合成类珍珠层矿物的普适型策略，通过构筑仿外套膜空间，利用空间内部的反应-扩散动力学及软物质协同效应共同引导”砖-泥“结构生成并优化构效关系。探索仿外套膜空间介导的多步相转变时空动力学及相关物理化学机制；结合仿外套膜空间的离子输运与多层次软物质动态组装行为，精准构筑宏观有序类珍珠层矿物多级结构；调控仿外套膜空间内部多尺度矿物-软物质界面相互作用，合理创制高性能仿生矿物。这不但有助于拓展绿色材料合成方法，也为深入探究生物矿化机制提供了思路。

To date, nacre is the mostly studied biogenic form, as it can reconcile resilience and strength by taking advantage of its “brick-and-mortar” architecture. Though a tremendous amount of nacre-mimic materials has been delivered via mineralization in layered scaffolds or ordered assembly of 2D nanoplatelets, efforts to impart self-organized, nacre-like materials nevertheless are almost unknown. Here we synthesize self-organized, nacre-like crystalline films via the organization of reaction-diffusion systems. The use of mantle-mimic compartments turns local deposition an oscillation system comprising the continuous diffusion of calcium cations in compartments and their periodic consumption ascribed to mineralization. The kinetic study, plus the structural and componential analyses of both mineralized and soft constituents, gives rise to our understanding of the structure-function relationship of nacre-like minerals. The fundamental insight gained from this self-organized system will significantly expand the toolbox of crystallization methods and allow the rational design of biomimetic hybrids with hierarchical architecture and related properties, and in a meantime, deepen our understanding of underlying mechanism of biomineralization.