三维分子印迹仿生膜的构筑及其在饮用水环境激素检测和去除中的应用

饮用水中痕量环境激素的快速检测和高效去除是环境科学亟需解决的重要问题。本项目拟将适配体和纳米多孔碳膜引入分子印迹技术中，构筑三维分子印迹仿生膜，将其作为环境激素的测定传感元件和去除膜，实现饮用水中酞酸酯类以及多氯联苯类典型环境激素的快速、灵敏、低成本检测和富集去除。项目利用适配体与分子印迹技术协同作用提高三维分子印迹仿生膜对环境激素的识别能力和适配体的稳定性；利用基于适配体的信号放大技术提高传感器的灵敏度；利用三维结构增加仿生膜对环境激素的富集容量和去除能力。项目将系统研究仿生膜的可控制备与表征、对环境激素的高效富集及快速灵敏的光电化学传感器的构建，明确适配体、分子印迹和三维结构协同作用与仿生膜的识别性能、富集容量、传感性能之间的关系和规律，阐明仿生膜对环境激素的识别、富集和测定机制。开展该项目将为监测和解决饮用水污染问题提供新思路，具有重要的科学意义和应用价值。

The rapid detection and efficient removal of trace environmental hormones in drinking water is an important issue in environmental science. In this project, aptamers and porous carbon membrane will be introduced into the molecular imprinting technology to build 3D molecular imprinting biomimetic membranes, which can be used as rapid, sensitive and low-cost sensors for the detection of environmental hormones such as phthalic acid esters and polychlorinated biphenyls in drinking water and removal membranes for the environmental hormones at the same time. The synergistic effect of aptamers and the molecular imprinting technology can improve the specific recognition ability of the biomimetic membranes to environmental hormones and the stability of aptamers. The signal amplification techniques of aptamers could improve the sensitivity of the sensors. The 3D structure of the membranes can increase their adsorption capacity and improve the sensitivity of the detection methods. The project will systematically study the preparation processes, the characterizations, and the applications of the 3D biomimetic membranes. The relationship between the coordination effects of aptamers, the molecular imprinting technology, the 3D structure and the specific recognition performance and enrichment capacity of the biomimetic membranes would be studied. The high-efficiency recognition ability, the enrichment and the detection mechanisms of the 3D membranes for environmental hormones would be clarified. This project will provide a new way for monitoring and solving the problem of drinking water pollution, which has important scientific significance and application value.