电极界面上荧光分子及其复合物或聚集体光致电荷转移的电分析化学研究

分子/原子的电子运动问题是化学学科的核心科学问题，光致电荷转移是光/电（分析）化学的重要分支。迄今，TiO2、CdS和钙钛矿等半导体的薄膜和纳米材料的光伏和光电化学研究报道甚多，但为数众多、可修饰性好的光致发光有机分子体系直接的（如导电材料表面的荧光猝灭、聚集诱导发光）光电化学研究报道甚少，尽管其深入研究有望为相关领域带来新的增长点。本项目中，我们拟研究荧光分子及其复合物或聚集体的荧光猝灭或增强过程中的光致电荷转移和光电化学行为，通过电化学、化学和光谱调制等方式，筛选和优化出具有高光电化学活性的荧光分子体系，据此实现一些生物标志物和生物活性小分子的生物亲和/催化型高性能光电化学分析传感，具有创新性、科学价值和应用前景。主要研究内容：（1）电极界面溶液态荧光分子的光致电荷转移，（2）电极界面荧光分子复合物或聚集体的光致电荷转移，（3）基于荧光分子及其复合物或聚集体光致电荷转移的光电化学分析。

The electron motion of molecules and atoms is the core scientific issue in chemistry discipline, and photoinduced charge (electron) transfer is an important branch of photochemistry and electrochemistry including photoanalytical and electroanalytical chemistry. So far, there are many reports on the photovoltaics and photoelectrochemistry of semiconductor films and nanomaterials of TiO2, CdS, perovskite and so on, but there are few reports on the direct photoelectrochemistry of so many photoluminescent organic molecular systems with easy chemical modification (such as fluorescence quenching on conductive materials and aggregation-induced emission), though their in-depth studies are expected to bring new growth points in relevant fields. In this project, we intend to study the photoinduced charge transfer and photoelectrochemical behavior in the process of fluorescence quenching or enhancement of fluorescent molecules and their composites or aggregates, and screen and optimize the fluorescent molecular systems with high photoelectrochemical activity by means of electrochemical, chemical and/or spectral modulation, so as to realize the bioaffinity/biocatalysis-based high-performance photoelectrochemical analysis/sensing of some biomarkers and bioactive small molecules. This project is of innovation, scientific value and application prospect. The main research contents are as follows: (1) photoinduced charge transfer of solution-state fluorescent molecules at electrode interface, (2) photoinduced charge transfer of fluorescent molecular composites or aggregates at electrode interface, and (3) photoelectrochemical analysis based on the photoinduced charge transfer of fluorescent molecules and their composites or aggregates.