基于Cassie-Baxter态润湿性梯度抗菌滑移表面自驱动细菌液滴的抗细菌黏附机制研究

有毒有害细菌在各类表面的不良黏附是导致人体传染和国家重大民生工程发生微生物腐蚀的重要起因，迄今为止，抗细菌黏附是一个全球挑战性课题，其技术理论和机制尚不完善。本项目提出具有自驱动细菌液滴效应的滑移抗菌表面能否获得高效的抗细菌黏附特性为科学假说，预实验发现Cassie-Baxter态的超疏水疏油表面具有优异的抗细菌黏附性，据此在技术层面上提出构建超疏水疏油-疏水疏油梯度润湿的抗菌滑移多级结构表面，从微纳结构、滑移特性、梯度润湿方面阐明其获得Cassie-Baxter态、低黏滞阻力和最大自驱动力的关键技术。在理论研究方面结合和拓展纯液滴定向输运理论，去研究二元复杂体系的细菌液滴在多级结构表面的自驱动运动规律和抗菌行为规律，以揭示具有自驱动效应的动态抗细菌黏附新机制。该项目的研究成果有助于为抗细菌黏附的构建提供重要的新方法与理论基础，且在应用层面上为实现在多类表面的抗细菌黏附提供关键数据。

Adverse adhesion of toxic and harmful bacteria on various surfaces is an important cause of human infection and microbial corrosion or pollution in national major projects and engineerings. So far, bacterial antiadhesion is a global challenging issue, and the theory and mechanism of bacterial antiadhesion are still not complete. This project puts forward a scientific hypothesis that whether driving bacteria droplets on the sliding antibacterial surface can obtain more efficient bacterial antiadhesion, our preliminary experiment demonatrates that the super-hydrophobic/oleophobic surface with Cassie-Baxter state has excellent resistance to bacterial adhesion. Thereby, from technical aspect, we further construct slipper and antibacterial surface of gradient wettability from super-hydrophobic/oleophobic to hydrophobic/oleophobic, and expound the key technology of obtaining Cassie Baxter state, low viscous resistance, and the biggest driving force. And from theoretical aspect, we also study the motion law of driving bacteria droplet in a binary complex system on the surface of the pluralistic structure by combining and extending of the directional transport theory of pure liquid droplets, so as to reveal the dynamic resistant bacterial antiadhesion mechanism of driving effect. The research results of this project will contribute to provide an important new method and theoretical basis for the construction of bacterial antiadhesion, and a key technical data for the realization of bacterial antiadhesion on various surfaces in the practical application.