天然有机物介导过硫酸盐光降解氟喹诺酮类抗生素机制研究

氟喹诺酮类抗生素（FQs）引起的水环境污染及生态毒性效应已成为我国乃至全球面临的重大环境问题。光降解作为FQs在自然水体中的一种重要消减方式，主要面临降解效率低、产物毒性强、抑制因素多等问题。近年来，基于过硫酸盐高级氧化技术（SR-AOPs）成为水污染控制领域的研究热点。但在无固体催化剂的天然水体环境中，过硫酸盐强化FQs光降解的研究鲜有报道。申请人前期研究发现在可见光条件下，腐殖酸能有效强化过硫酸盐氧化降解FQs。据此，本项目提出构建溶解性有机质（DOM）介导过硫酸盐强化FQs光降解体系，重点探究光子/电子在FQs、DOM和过硫酸盐之间的转移规律和路径，分析DOM强化FQs光降解效能与机制；探索FQs在过硫酸盐、DOM强化作用下的降解机理及路径；评估并调控FQs降解产物残留抗菌活性及生态毒性。项目的实施可为自然光消除FQs提供应用指导，同时为SR-AOPs在自然水体中的应用提供理论支撑。

The water environment pollution caused by fluoroquinolone antibiotics (FQs) and its ecotoxicological effects have become a significant environmental problem facing China and the world. Photodegradation as one of the main reduction approaches of FQs in natural waters, which faces the high toxicity of photodegradation products, low photodegradation efficiency, and many significant inhibition factors. Recently, advanced oxidation processes based on sulfate radicals (SR-AOPs) have been widely developed in water treatment. However, there is rarely a report on visible-light activated persulfate to enhance organic contaminant removal under natural water without solid-catalyst. Our previous study had found that humic acid can effectively enhance the oxidative degradation of FQs by persulfate under visible-light irradiation. In view of the above, we will propose to construct a FQs photodegradation system that persulfate mediated by DOM. The key of this work will explore the transfer law and path of photons/electrons between FQs, DOM and persulfate, and analyze the efficiency and mechanism of DOM enhancing FQS photodegradation. To further explore the degradation mechanism and pathways of FQs under the action of persulfate and DOM enhancement, the residual antimicrobial activity and ecotoxicity of FQs degradation products will be also assessed and regulated. The implementation of this project will guide the application of FQs photodegradation, and provide a powerful theoretical support for the utilization of SR-AOPs in water treatment.