Cryoablation in fibro-adipose vascular anomaly (FAVA): a minimally invasive treatment option
Cryoablation in fibro-adipose vascular anomaly (FAVA): a minimally invasive treatment option
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DOI：
10.1007/s00247-016-3576-0
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发表时间：
2016-07-01
影响因子：
2.3
通讯作者：
Spencer, Samantha A.
中科院分区：
文献类型：
--
作者：
Shaikh, Raja;Alomari, Ahmad I.;Spencer, Samantha A.
纤维脂肪血管异常（fafa）是一种复杂的血管畸形，通常表现为持续疼痛、不适、挛缩和其他致残症状。目前还没有微创治疗方案来有效控制这些症状。图像引导下的经皮冷冻消融术，已经用于控制癌症患者的疼痛，可以用于FAVA的类似适应症。目的：评价图像引导下经皮冷冻消融对faa病变症状控制的作用。2013年9月至2015年8月，我们对患有FAVA的20名儿童和年轻人进行了回顾性队列研究，他们在26个部位进行了经皮冷冻消融。结果基于简短疼痛量表评分（BPI）、并发症状、临床反应和患者满意度。冷冻消融后疼痛有明显改善，从3分（现在疼痛）下降到3.7分（最后24小时疼痛）。大多数患者表示，疼痛对他们日常社交生活的干扰较小。同时出现的肿胀、身体限制和皮肤过敏等症状也得到了改善。在冷冻消融后2-5个月的随访中，临床疗效最好，患者满意度较高。技术响应为100%。没有重大并发症。图像引导下经皮冷冻消融是治疗症状性FAVA病变的一种安全有效的选择。
Fibro-adipose vascular anomaly (FAVA) is a complex vascular malformation that typically presents with persistent pain, discomfort, contracture and other disabling symptoms. There are no minimally invasive treatment options to effectively control these symptoms. Image-guided percutaneous cryoablation, which has been used to control pain in people with cancer, could be used for similar indications in FAVA.To assess the role of image-guided percutaneous cryoablation for control of symptoms in FAVA lesions.We conducted a retrospective cohort study of 20 children and young adults with FAVA who underwent percutaneous cryoablation at 26 sites, from September 2013 to August 2015. The outcome was based on the brief pain inventory scoring (BPI), concurrent symptoms, clinical response and patient satisfaction.After cryoablation there was significant improvement in pain, which dropped by 3 points (pain now) to 3.7 points (pain in the last 24 h). Most patients indicated that pain interfered less in their everyday social life. Concurrent symptoms like swelling, physical limitations and skin hyperesthesia also improved. Clinical response was greatest at 2-5 months follow-up after cryoablation, with acceptable patient satisfaction thereafter. Technical response was 100%. There were no major complications.Image-guided percutaneous cryoablation is a safe and effective option for treatment of symptomatic FAVA lesions.