Regiospecific and stereoselective synthesis of functionalized and differently metalated alkenes by silyl- or stannylcupration of metalated acetylenes.
Regiospecific and stereoselective synthesis of functionalized and differently metalated alkenes by silyl- or stannylcupration of metalated acetylenes.
复制标题
通过金属化乙炔的甲硅烷基或甲锡烷基化来区域特异性和立体选择性合成官能化和不同金属化的烯烃。
DOI：
10.1002/chin.200129164
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发表时间：
2001
期刊：
影响因子：
--
通讯作者：
A. Sánchez,
中科院分区：
文献类型：
--
作者：
P. Cuadrado;A. M. González;A. Sánchez,
含甲硅烷基和锡的乙炔与一系列亲电子试剂（包括氯硅烷和氯锡烷）发生甲硅烷基或甲锡烷基化反应，得到不同金属化的乙烯基铜酸酯中间体，得到区域和立体定义的不同金属化的vic和偕甲硅烷基和锡三取代的烯烃。其中一些官能化多金属化烯烃是有机化学中有趣的合成子。
Differently metalated vinylcuprate intermediates resulting from silyl- or stannylcupration of silyl- and tin-containing acetylenes reacted with a range of electrophiles, including chlorosilanes and chlorostannanes, affording regio- and stereodefined differently metalated vic and gem silyl- and tin-trisubstituted alkenes. Some of these functionalized polymetalated olefins are interesting synthons in organic chemistry.