Transcranial direct current stimulation for treatment-resistant obsessive-compulsive disorder-A large case series
Transcranial direct current stimulation for treatment-resistant obsessive-compulsive disorder-A large case series
复制标题
经颅直流电刺激治疗难治性强迫症--一大系列病例
DOI：
10.1016/j.ajp.2021.102625
复制
发表时间：
2021-04-28
影响因子：
9.5
通讯作者：
Narayanaswamy, Janardhanan C.
中科院分区：
文献类型：
--
作者：
Thamby, Abel;Seshachala, Karthik;Narayanaswamy, Janardhanan C.
目的：本研究是一项大型病例系列研究，旨在评估经颅直流电刺激（tDCS）治疗难治性强迫症（OCD）的益处。方法：我们回顾了32例接受10-20次阳极SMA前tDCS治疗的难治性强迫症患者的病历。结果：总体而言，9例（28%）患者在10-20次治疗结束时显示出对tDCS的至少部分缓解[缓解者= 8例（25%），部分缓解者= 1例（3%）]。三分之二的部分应答者在10届会议结束时有反应，在20届会议结束时，结论：tDCS可能有利于一定比例的难治性强迫症患者。
Objective: The present study is a large case series evaluating the benefits of transcranial direct current stimulation (tDCS) in treatment-resistant obsessive compulsive disorder (OCD).Methods: We reviewed the charts of 32 patients with treatment-resistant OCD who received 10-20 sessions of anodal pre-SMA tDCS.Results: Overall, 9 (28 %) showed at least partial response to tDCS at the end of 10-20 sessions [responders = 8 (25 %), partial responders = 1 (3%)]. Two out of three partial responders at the end of 10 sessions had response at the end of 20 sessions.Conclusions: tDCS may benefit a proportion of patients with treatment-resistant OCD.