The use of molecular sieves to produce point sources of radioactivity.
The use of molecular sieves to produce point sources of radioactivity.
复制标题
使用分子筛产生放射性点源。
DOI：
10.1088/0031-9155/49/3/n02
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发表时间：
2004
影响因子：
3.5
通讯作者：
P. Roach
中科院分区：
文献类型：
--
作者：
D. Bailey;G. Snowdon;R. G. Cooper;P. Roach
我们使用市售分子筛（沸石）将放射性吸附到小珠（直径约2.1 mm）上，用于核医学的各种应用。将磁珠浸泡在约3GBq ml（-1）的[99 mTc]-NaTcO_4溶液中1-2分钟，可以产生总共含有3-6 MBq的点源。放射性摄取强烈依赖于珠粒大小。我们已经采用了伽马相机的均匀性和点源标记的解剖标志的交互式识别的源。由于它们的小尺寸（<<系统空间分辨率）、相对高的吸收和可忽略的散射贡献，它们提供了用于测量空间分辨率、检测器均匀性和能量分辨率的优异装置。分子筛是廉价的，并且容易与单光子和正电子发射放射性核素一起使用。
We have used commercially available molecular sieves (zeolites) to adsorb radioactivity onto small (approximately 2.1 mm diameter) beads for use in various applications in nuclear medicine. Soaking the beads in [99mTc]-NaTcO4 solution of approximately 3 GBq ml(-1) for 1-2 min can produce point sources containing 3-6 MBq total. Radioactive uptake was strongly dependent on bead size. We have employed the sources for gamma camera uniformity and as point source markers for interactive identification of anatomical landmarks. Due to their small size (<< system spatial resolution), relatively high uptake and negligible scattering contribution they provide excellent devices with which to measure spatial resolution, detector uniformity and energy resolution. The molecular sieves are inexpensive and readily usable with both single photon and positron emitting radionuclides.