New submonomers for poly N-substituted glycines (peptoids)
New submonomers for poly N-substituted glycines (peptoids)
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DOI：
10.1016/s0040-4039(98)02696-3
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发表时间：
1999-02-19
影响因子：
1.8
通讯作者：
Zuckermann, RN
中科院分区：
文献类型：
--
作者：
Uno, T;Beausoleil, E;Zuckermann, RN
Five protected submonomers for peptoid synthesis were prepared, including N-in-BOC-tryptamine, O-t-butyl tyramine, PMC-guanidino-propylamine, 6-amino-6-deoxy-D-galactopyranose diacetonide, and 5-amino-2,2-dimethyl-1,3-dioxane. The first three mimic natural aminoacid sidechains i.e, tryptophan, tyrosine, and arginine, while the last two provide hydrophilic sidechains. These submonomers were successfully used for preparation of oligo-peptoids by the submonomer synthesis method. (C) 1999 Elsevier Science Ltd. All rights reserved.
