ELECTRON-AFFINIC SENSITIZATION .I. A STRUCTURAL BASIS FOR CHEMICAL RADIOSENSITIZERS IN BACTERIA
ELECTRON-AFFINIC SENSITIZATION .I. A STRUCTURAL BASIS FOR CHEMICAL RADIOSENSITIZERS IN BACTERIA
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DOI：
10.1080/09553006914550741
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发表时间：
1969-01-01
期刊：
影响因子：
--
通讯作者：
COOKE, MS
中科院分区：
文献类型：
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作者：
ADAMS, GE;COOKE, MS
The bacteriumSerratia marcescenshas been used as a test system for demonstrating the radiosensitizing properties of a class of electron-affinic organic compounds. These include: unsaturated diesters and diketo compounds, mono-, di- and triketohydrindene (indanetrione), derivatives of pyruvic acid, quinones and several miscellaneous compounds. With few exceptions, the sensitization is restricted to anoxic systems. An electron-transfer mechanism, involving interaction of the sensitizer with a charged intermediate produced by direct energy absorption in a target molecule, is proposed as the basis of a model for radiosensitization.
