The three-spined stickleback-Schistocephalus solidus system: an experimental model for investigating host-parasite interactions in fish
The three-spined stickleback-Schistocephalus solidus system: an experimental model for investigating host-parasite interactions in fish
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DOI：
10.1017/s0031182009991466
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发表时间：
2010-03-01
期刊：
影响因子：
2.4
通讯作者：
Scharsack, J. P.
中科院分区：
文献类型：
--
作者：
Barber, I.;Scharsack, J. P.
假叶绦虫Schistocephalus solidus的Plerocercoids感染三棘鱼Gasterosteus aculeatus，对宿主鱼类的生物学产生重要影响。体外培养的寄生虫和产生的感染阶段，可用于感染刺鱼实验技术已经开发出来，该系统越来越多地被用作一个实验室模型，用于调查方面的主机-寄生虫相互作用。最近的实验室研究着重于宿主对感染的免疫反应、感染对宿主鱼类生长和生殖发育的后果以及感染对宿主行为的影响。在这里，我们介绍了主机和寄生虫，审查这些最近的实验感染研究的主要结果，并确定进一步的方面，可能会使用该系统进行调查的主机寄生虫的相互作用。
Plerocercoids of the pseudophyllidean cestode Schistocephalus solidus infect the three-spined stickleback Gasterosteus aculeatus, with important consequences for the biology of host fish. Techniques for culturing the parasite in vitro and generating infective stages that can be used to infect sticklebacks experimentally have been developed, and the system is increasingly used as a laboratory model for investigating aspects of host-parasite interactions. Recent experimental laboratory studies have focused on the immune responses of hosts to infection, the consequences of infection for the growth and reproductive development of host fish and the effects of infection on host behaviour. Here we introduce the host and the parasite, review the major findings of these recent experimental infection studies and identify further aspects of host parasite interactions that might be investigated using the system.