MORPHOMETRIC ANALYSIS OF FOLLICULAR DEVELOPMENT IN RAT

MORPHOMETRIC ANALYSIS OF FOLLICULAR DEVELOPMENT IN RAT
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DOI:
10.1095/biolreprod19.3.597
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发表时间:
1978-01-01
影响因子:
3.6
通讯作者:
MIDGLEY, AR
MIDGLEY, AR
中科院分区:
生物学2区
文献类型:
--
作者:
HIRSHFIELD, AN;MIDGLEY, AR

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Ovarian follicular development was examined in the cycling rat using histological techniques. The number and size distribution of follicles was determined for each day of the estrous cycle. While the number of follicles in the early stages of growth did not appear to vary dramatically throughout the estrous cycle, the final stages of growth and differentiation showed great variation throughout the cycle. No 390-500 .mu.m follicles were seen on proestrus, but many appeared the next day, suggesting that there was discontinuous follicle movement into the largest size range. Follicular atresia was most marked in follicles 200-400 .mu.m in diameter suggesting that there may be a critical stage during follicular development when most follicles become atretic unless rescued.