Cages Driven Away from Equilibrium Binding by Electric Fields
Cages Driven Away from Equilibrium Binding by Electric Fields
复制标题
电场驱使笼子脱离平衡结合
DOI：
10.1016/j.chempr.2019.04.020
复制
发表时间：
2019
期刊：
影响因子：
23.5
通讯作者：
Flood, Amar H.
中科院分区：
文献类型：
--
作者：
Dhara, Ayan;Flood, Amar H.
被推离平衡的分子和材料可以产生独特的动态和自适应特性，这些特性在静止时无法实现。在这一期的Chem中，Cockroft及其同事研究了配位笼与α-溶血素纳米口袋的瞬时结合和脱结合，并表明结合和脱结合事件被外部电场驱动脱离平衡。强施加的场可以反转笼-纳米孔结合选择性，并且可以增强对映体反转以使笼的一种手性形式相对于另一种手性形式富集。
Molecules and materials that are pushed away from equilibrium can produce unique dynamic and adaptive properties that cannot be attained when they are at rest. In this issue ofChem, Cockroft and co-workers study the transient binding and debinding of coordination cages to the nanopocket of α-hemolysin and show that the binding and debinding events are driven out of equilibrium by an external electric field. Strong applied fields can invert the cage-nanopore binding selectivities and can enhance enantio-inversion to enrich one chiral form of the cage over the other.